Boss Rush is a hidden playable mode in Drop Wizard. It unlocks when the player defeats Kardius' final form. Players control Mia and face the eleven boss battles fought throughout the game in succession.
Each level is set in the boss stage. The time is recorded when the player starts moving Mia, thus initiating the boss battle, and pauses when the boss is defeated. When a boss is defeated, the player is given a brief amount of time to collect fruit that was left behind from fallen enemies.
The player's total time is displayed upon successfully defeating the final boss.
Bosses are fought in the order they are encountered in the game.